ARIADNA: machine learning method for ancient DNA variant discovery.

doi:10.1093/dnares/dsy029

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Article

ARIADNA: machine learning method for ancient DNA variant discovery.

DNA research : an international journal for rapid publication of reports on genes and genomes - 1 Dec 2018

Kawash Joseph K, Smith Sean D, Karaiskos Spyros, Grigoriev Andrey

Abstract excerpt

Ancient DNA (aDNA) studies often rely on standard methods of mutation calling, optimized for high-quality contemporary DNA but not for excessive contamination, time- or environment-related damage of aDNA. In the absence of validated datasets and despite showing extreme sensitivity to aDNA quality, these methods have been used in many published studies, sometimes with additions of arbitrary filters or...

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PMID: 30215675
DOI: 10.1093/dnares/dsy029
PMCID: PMC6289774

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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