Article
CYP2D6 genotypes in revolving door patients with bipolar disorders: A case series.
Medicine - 1 Sept 2018
Seripa Davide, Lozupone Madia, Miscio Giuseppe, Stella Eleonora, La Montagna Maddalena, Gravina Carolina, Urbano Maria, di Mauro Lazzaro, Daniele Antonio, Greco Antonio, Logroscino Giancarlo, Panza Francesco, Bellomo Antonello
Abstract excerpt
RATIONALE: In psychiatric disorders, interindividual differences in cytochrome P450 (CYP)2D6 (CYP2D6) enzymatic activity could be responsible of adverse drug reactions (ADRs) and therapeutic failures (TFs) for CYP2D6-metabolized drugs, contributing to the periodical hospital readmissions of the revolving door (RD) condition. PATIENT CONCERNS: We investigated CYP2D6 genotypes in a controlled series of 5...
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