Article
Adolescent Inhalant Abuse Results in Adrenal Dysfunction and a Hypermetabolic Phenotype with Persistent Growth Impairments.
Neuroendocrinology - 1 Jan 2018
Crossin Rose, Andrews Zane B, Sims Natalie A, Pang Terence, Mathai Michael, Gooi Jonathan H, Stefanidis Aneta, Oldfield Brian J, Lawrence Andrew J, Duncan Jhodie R
Abstract excerpt
BACKGROUND/AIMS: Abuse of toluene products (e.g., glue-sniffing) primarily occurs during adolescence and has been associated with appetite suppression and weight impairments. However, the metabolic phenotype arising from adolescent inhalant abuse has never been fully characterised, and its persistence during abstinence and underlying mechanisms remain unknown. METHODS: Adolescent male Wistar rats (post-natal day...
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