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Article

Pharmacological management of X-linked hypophosphataemia.

British journal of clinical pharmacology - 1 Jun 2019

Imel Erik A, White Kenneth E

Abstract excerpt

The most common heritable disorder of renal phosphate wasting, X-linked hypophosphataemia (XLH), was discovered to be caused by inactivating mutations in the phosphate regulating gene with homology to endopeptidases on the X-chromosome (PHEX) gene in 1995. Although the exact molecular mechanisms by which PHEX mutations cause disturbed phosphate handling in XLH remain unknown, focus for novel therapies has more...

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Identifiers

PMID: 30207609
DOI: 10.1111/bcp.13763
PMCID: PMC6533442

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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