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Article

Omentin-regulated proteins combine a pro-inflammatory phenotype with an anti-inflammatory counterregulation in human adipocytes: A proteomics analysis.

Diabetes/metabolism research and reviews - 1 Jan 2019

Niersmann Corinna, Hauck Stefanie M, Kannenberg Julia M, Röhrig Karin, von Toerne Christine, Roden Michael, Herder Christian, Carstensen-Kirberg Maren

Abstract excerpt

AIMS: Experimental and epidemiological studies reported controversial data on the role of omentin in type 2 diabetes and cardiovascular diseases. This study aimed to characterise the impact of omentin on the secretome of human adipocytes to analyse the enrichment of these proteins in metabolic and cellular signalling pathways underlying its physiological function. MATERIAL/METHODS: Differentiated primary human...

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PMID: 30198166
DOI: 10.1002/dmrr.3074

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