Article
Genetic variability in coding regions of the surface antigen and reverse transcriptase domain of hepatitis B virus polymerase, Colombia, 2002-2014
Biomedica : revista del Instituto Nacional de Salud - 1 Aug 2018
Peláez-Carvajal Dioselina, Forero Nidia Janeth, Escalante-Mora Martha, Laiton-Donato Katherine, Usme-Ciro José Aldemar
Abstract excerpt
Introduction: Despite the availability of an effective vaccine and treatment to reduce the viral load and progressive hepatocellular injury, approximately 240 million people worldwide are chronically infected with the hepatitis B virus (HBV). In Colombia, the circulation of different viral genotypes has been confirmed. Mutations in the genome have been associated to antiviral therapy resistance, viral escape to...
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