Article
Prevalence of S282T mutation in different genotypes of hepatitis C virus from DAA-treated naïve Chinese patients who were chronically infected with HCV.
European review for medical and pharmacological sciences - 1 Aug 2018
Qiao B, Tong Y-Q, Wang M, Gong W-J, Li Y
Abstract excerpt
OBJECTIVE: Although direct-acting antiviral agents (DAAs) for treating hepatitis C virus (HCV) infection have not yet been approved for clinical application at present in China, the development trend is irresistible. DAAs-containing therapeutic regimens have been approved and others are also under development worldwide. In vitro studies have shown that S282T mutation in the NS5B region of HCV is involved in DAAs...
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