Article
Variants of the OLIG2 Gene are Associated with Cerebral Palsy in Chinese Han Infants with Hypoxic-Ischemic Encephalopathy.
Neuromolecular medicine - 1 Mar 2019
Sun Liya, Xia Lei, Wang Mingtai, Zhu Dengna, Wang Yangong, Bi Dan, Song Juan, Ma Caiyun, Gao Chao, Zhang Xiaoli, Sun Yanyan, Wang Xiaoyang, Zhu Changlian, Xing Qinghe
Abstract excerpt
Cerebral palsy (CP) is a leading cause of neurological disability among young children. Congenial and adverse perinatal clinical conditions, such as genetic factors, perinatal infection, and asphyxia, are risk factors for CP. Oligodendrocyte transcription factor (OLIG2) is a protein that is expressed in brain oligodendrocyte cells and is involved in neuron repair after brain injury. In this study, we employed a...
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