Genetic variants of interferon regulatory factor 5 associated with the risk of community-acquired pneumonia.

doi:10.1016/j.gene.2018.08.080

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Article

Genetic variants of interferon regulatory factor 5 associated with the risk of community-acquired pneumonia.

Gene - 30 Dec 2018

Wang Xiaohong, Guo Jia, Wang Ying, Xiao Yue, Wang Liying, Hua Shucheng

Abstract excerpt

Interferon regulatory factor 5 (IRF5) is a key transcription factor involved in the control of the expression of pro-inflammatory cytokines and immune responses to infection, and multiple polymorphisms of the IFR5 gene have been shown to be associated with autoimmune and infectious diseases. Several studies have investigated single nucleotide polymorphisms (SNPs) in a number of genes associated with the...

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PMID: 30176312
DOI: 10.1016/j.gene.2018.08.080

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.