Article
Comparative assessment of a metabolically attenuated Mycoplasma gallisepticum mutant as a live vaccine for the prevention of avian respiratory mycoplasmosis.
Vaccine - 7 Apr 2008
Gates A E, Frasca S, Nyaoke A, Gorton T S, Silbart L K, Geary S J
Abstract excerpt
In a previous study, signature sequence mutagenesis (SSM) was used to identify a mutant with a disruption of the gene encoding the metabolic factor, dihydrolipoamide dehydrogenase, and that mutant was designated Mg 7. The current study assessed the safety, immunogenicity and efficacy of Mg 7 in comparison to two commercially available vaccines (ts-11 and F) as well as a laboratory vaccine strain, GT5....
Topics
- Air Sacs
- Animals
- Antibodies, Bacterial
- Bacterial Vaccines
- Chickens
- Dihydrolipoamide Dehydrogenase
- Female
- Mutation
- Mycoplasma Infections
- Mycoplasma gallisepticum
- Poultry Diseases
- Respiratory Mucosa
- Respiratory Tract Infections
- Trachea