Article
Investigating possible causal effects of externalizing behaviors on tobacco initiation: A Mendelian randomization analysis.
Drug and alcohol dependence - 1 Oct 2018
Fluharty Meg E, Sallis Hannah, Munafò Marcus R
Abstract excerpt
Observational studies suggest childhood externalizing disorders are associated with increased smoking and earlier initiation. However, causality cannot be inferred from observational data alone. The current study uses two-sample MR to examine the causal relationship between externalizing behaviors and tobacco use. Single nucleotide polymorphisms (SNPs) associated with aggression were obtained from the Early Life...
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