Article
Epigenetics and Malaria Susceptibility/Protection: A Missing Piece of the Puzzle.
Frontiers in immunology - 1 Jan 2018
Arama Charles, Quin Jaclyn E, Kouriba Bourèma, Östlund Farrants Ann-Kristin, Troye-Blomberg Marita, Doumbo Ogobara K
Abstract excerpt
A better understanding of stable changes in regulation of gene expression that result from epigenetic events is of great relevance in the development of strategies to prevent and treat infectious diseases. Histone modification and DNA methylation are key epigenetic mechanisms that can be regarded as marks, which ensure an accurate transmission of the chromatin states and gene expression profiles over generations...
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