Article
Lower Circulating miR-122 Level in Patients with HNF1A Variant-Induced Diabetes Compared with Type 2 Diabetes.
Journal of diabetes research - 1 Jan 2018
Huang Xiuting, Gong Siqian, Ma Yumin, Cai Xiaoling, Zhou Lingli, Luo Yingying, Li Meng, Liu Wei, Zhang Simin, Zhang Xiuying, Ren Qian, Zhu Yu, Zhou Xianghai, Zhang Rui, Chen Ling, Gao Xueying, Zhang Fang, Wang Yanai, Han Xueyao, Ji Linong
Abstract excerpt
miR-122, the expression of which is regulated by several transcription factors, such as HNF1A, was recently reported to be associated with type 2 diabetes (T2DM) and hepatocellular carcinoma. HNF1A variants can cause diabetes and might be involved in the development of primary liver neoplasm. Differences in miR-122 expression among different types of diabetes have not been studied. This study aimed to investigate...
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