Article
Impact of the Localization of the Primary Tumor and RAS/BRAF Mutational Status on Maintenance Strategies After First-line Oxaliplatin, Fluoropyrimidine, and Bevacizumab in Metastatic Colorectal Cancer: Results From the AIO 0207 Trial.
Clinical colorectal cancer - 1 Dec 2018
Noepel-Duennebacke Stefanie, Arnold Dirk, Hertel Jan, Tannapfel Andrea, Hinke Axel, Hegewisch-Becker Susanna, Reinacher-Schick Anke
Abstract excerpt
INTRODUCTION: Numerous trials have examined the prognostic and predictive value of localization of the primary tumor (LPT) in metastastic colorectal cancer, there is limited information about the predictive value of LPT on different maintenance strategies. MATERIALS AND METHODS: We analyzed progression-free survival (PFS)/overall survival (OS) on maintenance therapy according to LPT and mutational subgroups...
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