Article
Anti-angiogenic effect of adiponectin in human primary microvascular and macrovascular endothelial cells.
Microvascular research - 1 Mar 2019
Palanisamy Karthikka, Nareshkumar Ragavachetty Nagaraj, Sivagurunathan Suganya, Raman Rajiv, Sulochana Konerirajapuram Natarajan, Chidambaram Subbulakshmi
Abstract excerpt
Neovascularization in retina and choroid involves interplay of many cytokines and growth factors. Vascular endothelial growth factor (VEGF) being a pro-angiogenic molecule has been found to be high in aqueous and vitreous humour of patients with proliferative diabetic retinopathy (PDR). VEGF is also found in the fibroblast and retinal pigment epithelial cells (RPE) of choroidal neovascular (CNV) membranes...
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