Article
ACE gene rs4343 polymorphism elevates the risk of preeclampsia in pregnant women.
Journal of human hypertension - 1 Dec 2018
Abedin Do Atieh, Esmaeilzadeh Emran, Amin-Beidokhti Mona, Pirjani Reihaneh, Gholami Milad, Mirfakhraie Reza
Abstract excerpt
The multifactorial basis of preeclampsia (PE) implies that there are several genes and risk factors that are important in the development of the disease. Therefore, the exact etiology and pathogenesis of preeclampsia remains unclear. It is suggested that inappropriate regulation of the renin-angiotensin system (RAS) is a risk factor for hypertension during pregnancy. The angiotensin I-converting enzyme (ACE)...
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