Harmonized Genome Wide Typing of Tubercle Bacilli Using a Web-Based Gene-By-Gene Nomenclature System.

doi:10.1016/j.ebiom.2018.07.030

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Article

Harmonized Genome Wide Typing of Tubercle Bacilli Using a Web-Based Gene-By-Gene Nomenclature System.

EBioMedicine - 1 Aug 2018

Kohl Thomas A, Harmsen Dag, Rothgänger Jörg, Walker Timothy, Diel Roland, Niemann Stefan

Abstract excerpt

BACKGROUND: Global tuberculosis (TB) control is challenged by uncontrolled transmission of Mycobacterium tuberculosis complex (Mtbc) strains, esp. of multidrug (MDR) or extensively resistant (XDR) variants. Precise analysis of transmission networks is the basis to trace outbreak M/XDR clones and improve TB control. However, classical genotyping tools lack discriminatory power due to the high similarity of strains...

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PMID: 30115606
DOI: 10.1016/j.ebiom.2018.07.030
PMCID: PMC6116475

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.