Article
Cell cycle-dependent force transmission in cancer cells.
Molecular biology of the cell - 15 Oct 2018
Panagiotakopoulou Magdalini, Lendenmann Tobias, Pramotton Francesca Michela, Giampietro Costanza, Stefopoulos Georgios, Poulikakos Dimos, Ferrari Aldo
Abstract excerpt
The generation of traction forces and their transmission to the extracellular environment supports the disseminative migration of cells from a primary tumor. In cancer cells, the periodic variation of nuclear stiffness during the cell cycle provides a functional link between efficient translocation and proliferation. However, the mechanical framework completing this picture remains unexplored. Here, the Fucci2...
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