SDH2 is involved in proper hypha formation and virulence in Candida albicans.

doi:10.2217/fmb-2018-0033

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Article

SDH2 is involved in proper hypha formation and virulence in Candida albicans.

Future microbiology - 1 Aug 2018

Bi Shuang, Lv Quan-Zhen, Wang Tian-Tian, Fuchs Beth Burgwyn, Hu Dan-Dan, Anastassopoulou Cleo G, Desalermos Athanasios, Muhammed Maged, Wu Chin-Lee, Jiang Yuan-Ying, Mylonakis Eleftherios, Wang Yan

Abstract excerpt

AIM: To investigate the role of SDH2 in Candida albicans filamentation and virulence. MATERIALS & METHODS: Caenorhabditis elegans and mouse candidiasis models were used to assess the virulence of a sdh2Δ/Δ mutant. Various hypha-inducing media were used to evaluate the hyphal development of C. albicans. DCFH-DA was used to measure intracellular Reactive Oxygen Species (ROS) levels. RESULTS: The sdh2Δ/Δ mutant was...

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PMID: 30113213
DOI: 10.2217/fmb-2018-0033
PMCID: PMC6161146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.