Article
Silence is golden: gene silencing of V. cholerae during intestinal colonization delivers new aspects to the acid tolerance response.
Gut microbes - 1 Jan 2019
Cakar Fatih, Zingl Franz G, Schild Stefan
Abstract excerpt
Bacterial pathogens of the gastrointestinal tract alter their expression profile upon ingestion by the host and activate a variety of factors enhancing colonization and virulence. However, gene silencing during infection might be as important as gene activation to achieve full colonization fitness. Thus, we developed and successfully applied a reporter technology to identify 101 in vivo repressed (ivr) genes of...
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