Relatedness disequilibrium regression estimates heritability without environmental bias.

doi:10.1038/s41588-018-0178-9

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Article

Relatedness disequilibrium regression estimates heritability without environmental bias.

Nature genetics - 1 Sept 2018

Young Alexander I, Frigge Michael L, Gudbjartsson Daniel F, Thorleifsson Gudmar, Bjornsdottir Gyda, Sulem Patrick, Masson Gisli, Thorsteinsdottir Unnur, Stefansson Kari, Kong Augustine

Abstract excerpt

Heritability measures the proportion of trait variation that is due to genetic inheritance. Measurement of heritability is important in the nature-versus-nurture debate. However, existing estimates of heritability may be biased by environmental effects. Here, we introduce relatedness disequilibrium regression (RDR), a novel method for estimating heritability. RDR avoids most sources of environmental bias by...

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PMID: 30104764
DOI: 10.1038/s41588-018-0178-9
PMCID: PMC6130754

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.