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Article

The interaction effects of polycyclic aromatic hydrocarbons exposure and TERT- CLPTM1L variants on longitudinal telomere length shortening: A prospective cohort study.

Environmental pollution (Barking, Essex : 1987) - 1 Nov 2018

Fu Wenshan, Chen Zhuowang, Bai Yansen, Wu Xiulong, Li Guyanan, Chen Weilin, Wang Gege, Wang Suhan, Li Xiaoliang, He Meian, Zhang Xiaomin, Wu Tangchun, Guo Huan

Abstract excerpt

Telomere length (TL) is an index of cellular aging and can predict the incidences of many age-related diseases. Change of TL might be affected by environmental pollution and individual's genetic background. In this cohort study, we aimed to evaluate the associations between polycyclic aromatic hydrocarbons (PAHs) exposure and longitudinal TL shortening, and investigate whether genetic variations in TERT-CLPTM1L...

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PMID: 30097281
DOI: 10.1016/j.envpol.2018.05.026

Genes

TERT
PAH

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