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Article

Global metabolomic responses in urine from atm deficient mice in response to LD50/30 gamma irradiation doses.

Environmental and molecular mutagenesis - 1 Aug 2018

Laiakis Evagelia C, Mak Tytus D, Strawn Steven J, Wang Yi-Wen, Moon Bo-Hyun, Ake Pelagie, Fornace Albert J

Abstract excerpt

Exposures to ionizing radiation (IR) may either be accidental or intentional, for medical purposes or even through terrorist actions. As certain populations emerge to be more radiosensitive than others, it is imperative to assess those individuals and treat them accordingly. To demonstrate the feasibility of rapid identification of such cases, we utilized the highly radiosensitive mouse model Atm-/- in the...

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Identifiers

PMID: 30095186
DOI: 10.1002/em.22202
PMCID: PMC6113093

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