Article
Radiation metabolomics. 1. Identification of minimally invasive urine biomarkers for gamma-radiation exposure in mice.
Radiation research - 1 Jul 2008
Tyburski John B, Patterson Andrew D, Krausz Kristopher W, Slavík Josef, Fornace Albert J, Gonzalez Frank J, Idle Jeffrey R
Abstract excerpt
Gamma-radiation exposure has both short- and long-term adverse health effects. The threat of modern terrorism places human populations at risk for radiological exposures, yet current medical countermeasures to radiation exposure are limited. Here we describe metabolomics for gamma-radiation biodosimetry in a mouse model. Mice were gamma-irradiated at doses of 0, 3 and 8 Gy (2.57 Gy/min), and urine samples...
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