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Article

The Overlap of Lung Tissue Transcriptome of Smoke Exposed Mice with Human Smoking and COPD

2 Aug 2018

Abstract excerpt

Abstract Genome-wide mRNA profiling in lung tissue from human and animal models can provide novel insights into the pathogenesis of chronic obstructive pulmonary disease (COPD). While 6 months of smoke exposure are widely used, shorter durations were also reported. The overlap of short term and long-term smoke exposure in mice is currently not well understood, and their representation of the human condition is...

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PMID: 30089872
DOI: 10.1038/s41598-018-30313-z

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