Article
Clinical Manifestations and Bacterial Genomic Analysis of Group A Streptococcus Strains That Cause Pediatric Toxic Shock Syndrome.
Journal of the Pediatric Infectious Diseases Society - 1 Jul 2019
Deniskin Roman, Shah Brittany, Muñoz Flor M, Flores Anthony R
Abstract excerpt
We report here 18 cases of pediatric group A streptococcal toxic shock syndrome, associated clinical findings, and bacterial molecular genetic characteristics discovered through whole-genome sequencing. This comparative whole-genome sequencing revealed unique gene content (speK) and polymorphisms (dpiB) in emm87 group A Streptococcus, the relative contributions of which, in combination with the host response, in...
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