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Article

Association analyses of eQTLs of the TYRO3 gene and allergic diseases in Japanese populations.

Allergology international : official journal of the Japanese Society of Allergology - 1 Jan 2019

Kanazawa Jun, Masuko Hironori, Yatagai Yohei, Sakamoto Tohru, Yamada Hideyasu, Kitazawa Haruna, Iijima Hiroaki, Naito Takashi, Saito Takefumi, Noguchi Emiko, Hirota Tomomitsu, Tamari Mayumi, Hizawa Nobuyuki

Abstract excerpt

BACKGROUND: TYRO3 is a member of the TAM (TYRO3, AXL, MERTK) receptor tyrosine kinase family and functions to limit type 2 immune responses implicated in allergic sensitization. Recent studies have shown that multiple intronic variants of TYRO3 were associated with asthma, implying that genetic variation could contribute to errant immune activation. We therefore hypothesized that expression quantitative trait...

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Identifiers

PMID: 30082152
DOI: 10.1016/j.alit.2018.07.004

Genes

TYRO3
AXL
MERTK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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