Article
Dabrafenib-trametinib combination in 'field-practice': an Italian experience.
Future oncology (London, England) - 1 Aug 2018
Depenni Roberta, De Rosa Francesco, Greco Stefano, Ridolfi Laura, Pellacani Giovanni, Ponti Giovanni, Cascinu Stefano, Guidoboni Massimo
Abstract excerpt
AIM: This observational study investigates the effectiveness and safety of dabrafenib/trametinib combination in patients with metastatic melanoma. PATIENTS & METHODS: Seventy-six patients treated with dabrafenib/trametinib (150 mg twice daily/2 mg once daily) were included. RESULTS: Median progression-free survival was 9 months (95% CI: 7-11) and median overall survival was 14 months (11-16); disease control rate...
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