Article
[BRAF-MEK inhibitor therapy in melanoma].
Magyar onkologia - 20 Jun 2022
Czirbesz Kata, Pánczél Gitta, Baranyai Fanni, Kispál Mihály, Tóth Erika, Bőcs Katalin, Balatoni Tímea, Fröhlich Georgina, Liszkay Gabriella
Abstract excerpt
We investigated the efficacy and safety of vemurafenib+cobimetinib (V+C) and dabrafenib+trametinib (D+T) based on real-life data. From 2015 and 2018 we have selected 118 BRAF-mutated metastatic melanoma patients, treated with V+C and D+T in our institute. We retrospectively analyzed the overall response rate (ORR), the progression-free survival (PFS), the overall survival (OS) and the adverse events of the...
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