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Article

Neuregulin1 acts as a suppressor in human lung adenocarcinoma via AKT and ERK1/2 pathway

1 Jun 2018

Abstract excerpt

BACKGROUND: Neuregulin1 (NRG1) is critical signaling protein that mediates the activation of downstream signaling pathways associated with malignancies. Multiple gene fusions related to NRG1 have been found in lung cancer. However, the underlying role NRG1 in lung cancer is yet unclear. Therefore, the present study investigated the biological functions on human lung adenocarcinoma (LUAD). METHODS: The expression...

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PMID: 30069312
DOI: 10.21037/jtd.2018.05.175

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