Article
Expressed HNSCC variants by HPV-status in a well-characterized Michigan cohort.
Scientific reports - 30 Jul 2018
Qin Tingting, Zhang Yanxiao, Zarins Katie R, Jones Tamara R, Virani Shama, Peterson Lisa A, McHugh Jonathan B, Chepeha Douglas, Wolf Gregory T, Rozek Laura S, Sartor Maureen A
Abstract excerpt
While whole-exome DNA sequencing is the most common technology to study genetic variants in tumors in known exonic regions, RNA-seq is cheaper, covers most of the same exonic regions, and is often more readily available. In this study, we show the utility of mRNA-seq-based variant analysis combined with targeted gene sequencing performed on both tumor and matched blood as an alternative when exome data is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
