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Article

Discovery of a Nitric Oxide Responsive Quorum Sensing Circuit in <i>Vibrio cholerae</i>

30 Jul 2018

Abstract excerpt

Group behavior of the human pathogen Vibrio cholerae, including biofilm formation and virulence factor secretion, is mediated by a process known as quorum sensing. Quorum sensing is a way by which bacteria coordinate gene expression in response to population density through the production, secretion, and detection of small molecules called autoinducers. Four autoinducer-mediated receptor histidine kinases have...

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PMID: 30060647
DOI: 10.1021/acschembio.8b00360

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