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Regulation of the human placental (pro)renin receptor-prorenin-angiotensin system by microRNAs

27 Jul 2018

Abstract excerpt

STUDY QUESTION: Are any microRNAs (miRNAs) that target the placental renin-angiotensin system (RAS) in the human placenta suppressed in early gestation? SUMMARY ANSWER: Overall, 21 miRNAs with predicted RAS mRNA targets were less abundant in early versus term placentae and nine were more highly expressed. WHAT IS KNOWN ALREADY: Regulation of human placental RAS expression could alter placental development and...

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Share to MicroRNA in disease regulation
Share to Pregnancy and preeclampsia studies
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PMID: 30060096
DOI: 10.1093/molehr/gay031

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