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Article

Decreased microbiome diversity in the HIV small airway epithelium

27 Jul 2018

Abstract excerpt

BACKGROUND: Persons living with human immunodeficiency virus (PLWH) face an increased burden of chronic obstructive pulmonary disease (COPD). Repeated pulmonary infections, antibiotic exposures, and immunosuppression may contribute to an altered small airway epithelium (SAE) microbiome. METHODS: SAE cells were collected from 28 PLWH and 48 HIV- controls through bronchoscopic cytologic brushings. DNA extracted...

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PMID: 30053882
DOI: 10.1186/s12931-018-0835-7

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