Article
Unperturbed expression bias of imprinted genes in schizophrenia.
Nature communications - 25 Jul 2018
Gulyás-Kovács Attila, Keydar Ifat, Xia Eva, Fromer Menachem, Hoffman Gabriel, Ruderfer Douglas, Sachidanandam Ravi, Chess Andrew
Abstract excerpt
How gene expression correlates with schizophrenia across individuals is beginning to be examined through analyses of RNA-seq from postmortem brains of individuals with disease and control brains. Here we focus on variation in allele-specific expression, following up on the CommonMind Consortium (CMC) RNA-seq experiments of nearly 600 human dorsolateral prefrontal cortex (DLPFC) samples. Analyzing the extent of...
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