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Identification of a novel tri-genotypic recombinant Hepatitis B virus in Bangladesh.

Virus research - 15 Aug 2018

Shaha Modhusudon, Hadisur Rahman Md, Jahan Munira, Dey Shuvra Kanti, Das Keshob Chandra, Hashem Abu, Salimullah Md

Abstract excerpt

We report a novel tri-genotypic recombinant Hepatitis B virus (HBV) strain circulating in Bangladesh. The strain is recombinant with the genotypes D, C and E, of which, genotype E was not reported before in Bangladesh. Additionally, the complete genome has a frameshift deletion of nine nucleotides from overlapping Surface and Polymerase genes, and a vaccine escape mutation, A128 V, in the surface protein. This is...

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PMID: 30040979
DOI: 10.1016/j.virusres.2018.07.014

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