Article
Single olfactory receptors set odor detection thresholds.
Nature communications - 23 Jul 2018
Dewan Adam, Cichy Annika, Zhang Jingji, Miguel Kayla, Feinstein Paul, Rinberg Dmitry, Bozza Thomas
Abstract excerpt
In many species, survival depends on olfaction, yet the mechanisms that underlie olfactory sensitivity are not well understood. Here we examine how a conserved subset of olfactory receptors, the trace amine-associated receptors (TAARs), determine odor detection thresholds of mice to amines. We find that deleting all TAARs, or even single TAARs, results in significant odor detection deficits. This finding is not...
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