Influence of odorant receptor repertoire on odor perception in humans and fruit flies.

doi:10.1073/pnas.0605321104

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Article

Influence of odorant receptor repertoire on odor perception in humans and fruit flies.

Proceedings of the National Academy of Sciences of the United States of America - 27 Mar 2007

Keller Andreas, Vosshall Leslie B

Abstract excerpt

The olfactory system is thought to recognize odors with multiple odorant receptors (ORs) that are activated by overlapping sets of odorous molecules, ultimately generating an odor percept in the brain. We investigated how the odor percept differs between humans and Drosophila melanogaster fruit flies, species with very different OR repertoires. We devised high-throughput single fly behavior paradigms to ask how a...

Topics

Alleles
Animals
Drosophila Proteins
Drosophila melanogaster
Humans
Models, Genetic
Odorants
Olfactory Pathways
Perception
Psychophysics
Receptors, Odorant
Sensitivity and Specificity
Smell
Species Specificity
Time Factors

Source

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Identifiers

PMID: 17372215
DOI: 10.1073/pnas.0605321104
PMCID: PMC1838502

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