Article
Neuroendocrine and immune disequilibrium as a probable link between metabolic syndrome and carcinogenesis.
Medical hypotheses - 1 Sept 2018
Hristova Mariyana G
Abstract excerpt
Numerous investigations prove a higher incidence of carcinogenesis in metabolic syndrome (MetS). They indicate the important role of obesity, elevated inflammatory biomarkers, hyperinsulinemia, hyperglycemia, and dyslipidemia as well. Elevated plasma insulin and free insulin-like growth factor-1 (IGF-1) levels stimulate cell proliferation. The present publication considers the role of neuroendocrine and immune...
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