Article
Variables affecting penetrance of gastric and duodenal phenotype in familial adenomatous polyposis patients.
BMC gastroenterology - 16 Jul 2018
Sample Danielle C, Samadder N Jewel, Pappas Lisa M, Boucher Kenneth M, Samowitz Wade S, Berry Therese, Westover Michelle, Nathan Deepika, Kanth Priyanka, Byrne Kathryn R, Burt Randall W, Neklason Deborah W
Abstract excerpt
BACKGROUND: Patients with familial adenomatous polyposis (FAP) frequently undergo colectomy to reduce the 70 to 90% lifetime risk of colorectal cancer. After risk-reducing colectomy, duodenal cancer and complications from duodenal surgeries are the main cause of morbidity. Our objective was to prospectively describe the duodenal and gastric polyp phenotype in a cohort of 150 FAP patients undergoing pre-screening...
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