Article
Molecular characterization of Hb H disease in southern Thailand.
International journal of hematology - 1 Oct 2018
Nittayaboon Kesara, Nopparatana Chamnong
Abstract excerpt
Genotypes of 260 individuals with hemoglobin H (Hb H) disease originating from various provinces in southern Thailand were characterized by multiplex PCR (M-PCR) and reverse dot blot hybridization (RDB). M-PCR was used to amplify target fragments and then hybridized with allele-specific oligonucleotide (ASO) probes which were bound on a nylon membrane. A total of eight α-thalassemia (α-thal) mutations, which...
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