Article
Analytical "bake-off" of whole genome sequencing quality for the Genome Russia project using a small cohort for autoimmune hepatitis.
PloS one - 1 Jan 2018
Zhernakova Daria V, Kliver Sergei, Cherkasov Nikolay, Tamazian Gaik, Rotkevich Mikhail, Krasheninnikova Ksenia, Evsyukov Igor, Sidorov Sviatoslav, Dobrynin Pavel, Yurchenko Andrey A, Shimansky Valentin, Shcherbakova Irina V, Glotov Andrey S, Valle David L, Tang Minzhong, Shin Emilia, Schwarz Kathleen B, O'Brien Stephen J
Abstract excerpt
A comparative analysis of whole genome sequencing (WGS) and genotype calling was initiated for ten human genome samples sequenced by St. Petersburg State University Peterhof Sequencing Center and by three commercial sequencing centers outside of Russia. The sequence quality, efficiency of DNA variant and genotype calling were compared with each other and with DNA microarrays for each of ten study subjects. We...
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