Suppression of PROX1-mediated TERT expression in hepatitis B viral hepatocellular carcinoma.

doi:10.1002/ijc.31731

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Article

Suppression of PROX1-mediated TERT expression in hepatitis B viral hepatocellular carcinoma.

International journal of cancer - 15 Dec 2018

Kim Young-Joo, Yoo Jeong Eun, Jeon Youngsic, Chong Jae Uk, Choi Gi Hong, Song Dae-Geun, Jung Sang Hoon, Oh Bong-Kyeong, Park Young Nyun

Abstract excerpt

Somatic mutations in the telomerase reverse transcriptase (TERT) promoter are related to telomerase activation and frequently occur at two hot spots located at -124 and -146 bp relative to the start codon in various cancers. Here, we investigated the occurrence and implications of genetic alterations in the TERT promoter in hepatitis B viral hepatocellular carcinoma (B viral HCC). TERT promoter mutations,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 29987895
DOI: 10.1002/ijc.31731

Genes

TERT
PROX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.