Article
Genetics of Lipodystrophy: Can It Help in Understanding the Pathophysiology of Metabolic Syndrome?
Biomolecules - 6 Jul 2018
Mathur Sandeep Kumar, Tiwari Pradeep, Gupta Sonal, Gupta Nidhi, Nimesh Surendra, Medicherla Krishna Mohan, Suravajhala Prashanth
Abstract excerpt
Understanding phenotypes and their genetic determinants for metabolic syndrome (MetS) has been quite challenging. With the advent of systems genomic approaches, there is a need to decipher methods for identification and evaluating the functional role of phenotypic traits associated with complex diseases, such as MetS. The monogenic syndromes of lipodystrophy are well understood, but the molecular pathophysiology...
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