Rpd3L HDAC links H3K4me3 to transcriptional repression memory.

doi:10.1093/nar/gky573

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Article

Rpd3L HDAC links H3K4me3 to transcriptional repression memory.

Nucleic acids research - 19 Sept 2018

Lee Bo Bae, Choi Ahyoung, Kim Ji Hyun, Jun Yukyung, Woo Hyeonju, Ha So Dam, Yoon Chae Young, Hwang Jin-Taek, Steinmetz Lars, Buratowski Stephen, Lee Sanghyuk, Kim Hye Young, Kim TaeSoo

Abstract excerpt

Transcriptional memory is critical for the faster reactivation of necessary genes upon environmental changes and requires that the genes were previously in an active state. However, whether transcriptional repression also displays 'memory' of the prior transcriptionally inactive state remains unknown. In this study, we show that transcriptional repression of ∼540 genes in yeast occurs much more rapidly if the...

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PMID: 29982589
DOI: 10.1093/nar/gky573
PMCID: PMC6144869

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.