Article
Assessing Plasmodium falciparum transmission in mosquito-feeding assays using quantitative PCR
5 Jul 2018
Abstract excerpt
BACKGROUND: Evaluating the efficacy of transmission-blocking interventions relies on mosquito-feeding assays, with transmission typically assessed by microscopic identification of oocysts in mosquito midguts; however, microscopy has limited throughput, sensitivity and specificity. Where low prevalence and intensity mosquito infections occur, as observed during controlled human malaria infection studies or natural...
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