Article
The interplay between mutations in cagA, 23S rRNA, gyrA and drug resistance in Helicobacter pylori.
Revista do Instituto de Medicina Tropical de Sao Paulo - 1 Jan 2018
Vianna Júlia Silveira, Ramis Ivy Bastos, Ramos Daniela Fernandes, Gastal Otávio Leite, Silva Renato Azevedo da, Gonçalves Carla Vitola, Silva Pedro Eduardo Almeida da
Abstract excerpt
In this study, we evaluated the mutations of Helicobacter pylori associated with resistance to clarithromycin and levofloxacin. Furthermore, based on the proposed interaction between antimicrobial resistance and pathogenicity, we correlated the mutation profiles of the strains with the presence of the pathogenicity gene cagA. We analyzed 80 gastric biopsy specimens from H. pylori-infected patients for point...
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