Article
Neuropsychiatric Aspects in Men with Klinefelter Syndrome.
Endocrine, metabolic & immune disorders drug targets - 1 Jan 2019
Giagulli Vito Angelo, Campone Beatrice, Castellana Marco, Salzano Ciro, Fisher Alessandra Daphne, de Angelis Cristina, Pivonello Rosario, Colao Annamaria, Pasquali Daniela, Maggi Mario, Triggiani Vincenzo, On Behalf Of The Klinefelter ItaliaN Group King
Abstract excerpt
BACKGROUND AND OBJECTIVE: Klinefelter Syndrome (KS) is the most common sex chromosome aneuploidy (47, XXY) and cause of male hypergonadotropic hypogonadism. It is characterized by an extreme clinical heterogeneity in presentation, including infertility, hypogonadism, language delay, metabolic comorbidities, and neurocognitive and psychiatric disorders. Since testosterone is known to have organizational,...
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