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Article

DNA Methylation of Proximal PLAT Promoter in Chronic Rhinosinusitis With Nasal Polyps

2 Jul 2018

Abstract excerpt

Background Nasal polyps (NP) are characterized by pseudocysts derived from stromal tissue edema and cause persistent infections in patients with chronic rhinosinusitis (CRS). A low level of tissue-type plasminogen activator (gene name PLAT) is considered a cause of stromal tissue edema because of insufficient plasmin activation in NP; however, the mechanism regulating PLAT gene expression levels is still unclear....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29962211
DOI: 10.1177/1945892418782236

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