Comparative study of microRNA profiling in one Chinese Family with PSEN1 G378E mutation.

doi:10.1007/s11011-018-0279-2

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Article

Comparative study of microRNA profiling in one Chinese Family with PSEN1 G378E mutation.

Metabolic brain disease - 1 Oct 2018

Lv Zhanyun, Hu Liangchen, Yang Yan, Zhang Kui, Sun Zuzhen, Zhang Jing, Zhang Lipan, Hao Yanlei

Abstract excerpt

MicroRNAs are not widely studied in familial Alzheimer's disease cases, whether the microRNA profilings in familial Alzheimer's disease patients are similar to the sporadic AD patients is not known. This study aims to investigate the differential expression of microRNAs (miRNAs) associated with early-onset familial Alzheimer's disease (EO-FAD) in a Chinese family. We performed the gene mutation analysis in a...

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Identifiers

PMID: 29961914
DOI: 10.1007/s11011-018-0279-2

Genes

PSEN1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.